Advances in Infection Animal Models of Enterovirus 71

doi:10. 3969 / j. issn. 1006-6179. 2022. 02. 015

Laboratory Animal Science ›› 2022, Vol. 39 ›› Issue (2): 91-94.DOI: 10. 3969 / j. issn. 1006-6179. 2022. 02. 015

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Advances in Infection Animal Models of Enterovirus 71

( National Institutes for Food and Drug Control, Beijing 102629, China)

Received:2021-04-05 Online:2022-04-28 Published:2022-05-16

EV71 动物模型研究进展

(中国食品药品检定研究院,北京 102629)

通讯作者: 范昌发( 1970—) ,男,博士 / 研究员,从事疾病动物模型研究. E-mail:fancf@ nifdc. org. cn
作者简介:吴勇( 1984—) ,男,硕士 / 实习研究员,从事传染病动物模型研究. E-mail:wuyong@ nifdc. org. cn
基金资助:
重要致病原及突变株的疫苗及药物有效性评价的动物模型体系建设和应用( 2021YFC2301700) ;新发突发重大传染病动物模型的构建及标准化( 2017ZX10304402-002)

Abstract

Abstract:

Abstract:human enterovirus 71 ( EV71 ) is the causative agent associated with hand foot and mouth disease ( HFMD) , and be found to be neurotropic. The worldwide spread of EV71 has drawn increasing attention from researchers and medical professionals. Animal model is an important means to study infectious diseases, at present many result have been obtained on EV71 susceptible animal models. In this study we summarized the current research on EV71 animal models and focus on the future research direction.

Key words:

Key words:HFMD, enterovirus 71, animal models

摘要：

摘要:人肠道病毒 71 型( enterovirus 71,EV71) 能够引起儿童的手足口病,并且具有嗜神经毒性。该病症在全球范围内的传播逐渐引起科研和医务人员的重视。动物模型是研究传染病的重要手段,现阶段对 EV71 易感动物模型研究有了多方面成果。本文对 EV71 动物模型近期的研究进行整理总结,并对后续研究方向进行展望。

关键词:

关键词: 手足口病, 肠道病毒 71 型, 动物模型

CLC Number:

WU Yong, XIONG Rui, FAN Changfa.

Advances in Infection Animal Models of Enterovirus 71 [J]. Laboratory Animal Science, 2022, 39(2): 91-94.

吴勇, 熊芮, 范昌发.

EV71 动物模型研究进展 [J]. 实验动物科学, 2022, 39(2): 91-94.

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Advances in Infection Animal Models of Enterovirus 71

EV71 动物模型研究进展

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